AA-004 - A biomimetic device combining microfluidics with nanotechnology allows studying the adhesion of erythrocytes to blood vessels.
Saffioti, N.A.1; Leal Denis, M.F.2; Herlax V.3; Schwarzbaum P.J.2; Pallarola D.1
1Instituto de Nanosistemas, Universidad Nacional de San Martín, Argentina; 2Instituto de Química y Fisicoquímica Biológicas (IQUIFIB) CONICET/UBA, Argentina 3INIBIOLP, Facultad Ciencias Médicas, UNLP, Argentina.
BA-003 - Transitions During the Voltage Sensor Activation in the Voltage-gated Proton Channel (Hv1) Changed According to the Absolute pH
Emerson M. Carmona1, Osvaldo Alvarez1,2, Alan Neely1, Carlos Gonzalez1.
1Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso, Chile, 2Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile
BA-012 - Steady state kinetic analysis of Legionella pneumophila Cu+ transport ATPase. The activation by Cu+ and ATP
Placenti, M.A.1,2; Roman, E.A.2,3; González Flecha F.L.1,2; González Lebrero R.M.1,2
1Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Depto de Química Biológica, Buenos Aires, Argentina; 2Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas, Buenos Aires, Argentina; 3Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Depto de Química Biológica, Buenos Aires, Argentina.
CB-013 - Toxicity evaluation of Bauhinia monandra extract containing phytochemicals and leaf lectin (BmoLL) on embryos of Biomphalaria glabrata
Aguiar, T.W.A.1, Ferreira, S.A.O.2, Freitas, K.H.1, Santos, L.S.1, Ferreira, M.R.A.3, Soares, L.A.L.3, Melo, A.M.M.A.4, Albuquerque, M.C.P.A.5, Araújo, H.D.A.1, Aires, A.L.5, Coelho, L.C.B.B.1
1Depto de Bioquímica, Univ. Federal de Pernambuco (UFPE), Recife, PE, Brazil; 2Centro Acadêmico de Vitória, UFPE, Recife, PE, Brazil; 3Depto de Ciências Farmacêuticas, UFPE, Recife, PE, Brazil; 4Depto de Biofísica e Radiobiologia, UFPE, Recife, PE, Brazil; 5Depto de Medicina Tropical, UFPE, Recife, PE, Brazil.
CD-014 - A new arylsulfanyl-benzo-2,1,3- thiadiazoles derivative has anti-amnesic effect on behavioral in mice
Rodrigues, K.C.1; Fronza, M.G. 2; Savegnago L. 2; Santos, B.F. 3; Domingues, N.L.C.3; Wilhelm, E.A.1; Luchese, C.1
1Programa de pós graduação em Bioquímica e Bioprospecção, Lab. de pesquisa em Farmacologia Bioquímica (LaFarBio), Centro de Ciências Químicas, Farmacêuticas e de alimentos, Univ. Federal de Pelotas (UFPel), Pelotas, RS, Brasil.; 2Programa de Pós-Graduação em Biotecnologia, GPN, Centro de Desenv. Tecnológico, UFPel, Pelotas, RS, Brazil. 3Lab. de Catálise Orgânica e Biocatálise, Univ. Federal de Grande Dourados, Dourados/ MS, Brasil.
CD-017 - Aging aggravates acute oxaliplatin-induced peripheral neuropathy in mice through of the increase of the oxidative stress and modulation of Na+, K+ - ATPase: Beneficial effects of 7-Chloro-4-(phenylselanyl) quinoline
Chaves, J. S.1; Reis, A. S.2; Martins, C. C.²; Da Mota, H. P.³; Do Sacramento, M.³; Alves, D3.; Luchese, C.²; Wilhelm, E.A.²
¹Curso de Farmácia, Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Univ. Federal de Pelotas, RS, Brazil; 2Programa de Pós-graduação em Bioquímica e Bioprospecção,Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Univ. Federal de Pelotas, RS, Brazil; ³Programa de Pós-graduação em Química, Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Univ. Federal de Pelotas, RS, Brazil.
CD-044 - PEGylated liposomal formulation of amphotericin B for improved treatment of cutaneous lesihmaniasis
Ramos, G.S1; Vallejos, V.M.R1; Borges, G.S.M3; Fujiwara, R.T2; Ferreira, L.A.M3; Guimaraes, P.P.G.1; Frézard, F1.
1Departamento de Fisiologia e Biofísica, 2Departamento de Parasitologia, Instituto de Ciências Biológicas; 3Faculdade de Farmácia, Universidade Federal de Minas Gerais, MG, Brazil
CD-047 - Hybrid Nanoemulsions for Migraine Treatment
Ribeiro, L.N.M.1; Couto, V.M.1; Castro, S.R.1; Rodrigues de Silva, G.H.1; Breitkreitz, M.C.2; Martinez,C.S.3; Igartúa, D.E.3; Prieto, M.J.3; de Paula, E1.
1 Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil; 2 Department of Analytical Chemistry, Institute of Chemistry, University of Campinas, Campinas, SP, Brazil; 3 Department of Science and Technology, National University of Quilmes, Bernal, Buenos Aires, Argentina.
DA-007 - Biochemical and Biophysical studies of the Neurospora crassa AAA+ RVB-1/RVB-2 protein complex and its novel function in stress response
Campanella, J.E.M.1, Kiraly, V.T.R.2, Barbugli, P.A.3, Gomes, A.A.S.4, Fontes, M.R.M.4, Borges, J.C.2, Bertolini, M.C.1
1Depto de Bioquímica e Química Orgânica, Instituto de Química, Univ. Estadual Paulista, Araraquara, SP, Brazil; 2Depto de Química e Física Molecular, Instituto de Química, Univ. de São Paulo, São Carlos, SP, Brazil; 3Depto de Materiais Dentários e Prótese, Faculdade de Odontologia, Univ. Estadual Paulista, Araraquara, SP, Brasil; 4Depto de Física e Biofísica, Instituto de Biociências, Univ. Estadual Paulista, Botucatu, SP, Brazil
DA-015 - Preliminary over view of the interaction features between the recombinant disintegrin, Jararacin, and platelets: NMR studies
Chang, J.E.; Vasconcelos, A; David, V.; Machado, L; Zingali, R.B.; Almeida, F.C.L.
Universidade Federal do Rio de Janeiro, Instituto de Bioquímica Médica Leopoldo de Meis, RJ, Brazil
DA-026 - Biochemical characterization and structure elucidation of a new cytochrome P450 decarboxylase
Rade, L.L1.; de Sousa, A.S.1; Das, S.2; Generoso, W.C.1; Ávila M.C.1; Vieira, P.S.1; Persinoti, G.F.1; Bonomi,A.1; Murakami, M.T.1; Makris, T.M.2; Zanphorlin, L.M.1
1Brazilian Biorenewables National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, Brazil; 2Molecular and Structural Biochemistry, North Carolina State University, Raleigh, USA
DA-029 - Criteria for the Development of Structurally Functional Humanized Antibody Molecules
Jiacomini, I.G.1; Beltramino, M.1; Minozzo, J.C.4 ; de Moura, J.F.1; Billiald, P.3; Aubrey, N.2; Alvarenga,L.M.1
1Laboratório de Imunoquímica, Departamento de Patologia Básica, Universidade Federal do Paraná, Paraná, Brazil; 2INRA, UMR 1282, Faculté de Pharmacie, Université de Tours, Tours, France; 3IPSIT, School of Pharmacy, University Paris-Saclay, Châtenay-Malabry, France. 4CPPI – Centro de Pesquisa e Produtos Imunobiológicos, Piraquara, Brazil.
DA-068 - Mechanism elucidation of not conventional peroxygenases applied on production of drop-in biofuels
Ávila, M. C.1; Sousa, A.1, Rade, L.1, Generoso, W.1, Miyamoto, R.1, Ramos, C.2, Persinoti, G1, Makris,T.3, Vieira, P. S.1, Zanphorlin, L. M.1
1Brazilian Biorenewables National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil; 2Chemestry Institute, University of Campinas (UNICAMP), Campinas, Brazil; 3Molecular and Structural Biochemistry (NCSU), North Carolina State University, Raleigh, USA
DB-014 - Druggable hot spots in the dimerization interface of trypanothione reductase enzyme from trypanosomatids.
Olívia Teixeira1, Pedro Lacerda2, Thamires Quadros Froes1, Marcelo Santos Castilho2, Maria Cristina Nonato1.
1Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, SP, Brasil. 2Faculdade de Farmácia da Universidade Federal da Bahia, Salvador, BA, Brasil.
EA-007 - Glucocorticoids decrease the thermogenic capacity and increase the triacylglycerol synthesis by glycerokinase activation in brown adipose tissue of rats
Assis, A. P1; Silva, K. E.1, Lautherbach, N. E. S.1, Garófalo, M. A. R.2, Zanon, N. M.2, Navegantes, L. C. C.2, Chaves, V. E.3, Kettelhut, I. C.1
1Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. 2Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. 3Laboratory of Physiology, Federal University of São João del-Rei, Divinópolis, MG, Brazil.
EA-008 - High-density lipoprotein remodeling associates with COVID-19 severity: a quantitative proteomic study
Souza Jr, D.R.1; Silva, A.R.M.1; Rosa-Fernandes, L2.; Palmisano, G.2; Ronsein, G.E.1
1Depatment of Biochemistry, Chemistry Institute, University of São Paulo, SP, Brazil.; 2Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, SP, Brazil.
EA-018 - Overexpression of the argonaute ALG-1 induces miRNA biogenesis and promotes oxidative stress resistance in C. elegans
Vergani Junior, C. A.*1; Moro, R. P.*1; Knittel, T. L.1; Pinto, S. S.1; De Souza, E. A.1; Massirer, K. B.1; Mori,M. A.1
1Departamento de Bioquímica e Biologia Tecidual, Instituto de Biologia Universidade Estadual de Campinas, Campinas, SP, Brazil. * contributed equally.
EB-015 - Fetuin detection by a promising optical-magnetic multimodal nanoprobe functionalized with Cramoll lectin
Oliveira, W.F.1,2, Cabrera, M.P.3, Lima, J.V.A.2, Coelho, L.C.B.B.1, Pereira, G.A.L.3, Santos, B.S.4, Cabral Filho, P.E.2, Correia, M.T.S.1, Fontes, A.2
1Depto de Bioquímica, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil; 2Depto de Biofísica e Radiobiologia, UFPE, Recife, PE, Brazil; 3Depto de Química Fundamental, UFPE, Recife, PE, Brazil; 4Departamento de Farmácia, UFPE, Recife, PE, Brazil.
FB-004 - Biochemical implementation of optimal control for run-and-tumble chemotaxis
Kento Nakamura.1; Tetsuya J. Kobayashi1,2,3
1Graduate school of Information Science and Technology, University of Tokyo, Tokyo, Japan; 2Institute of Industrial Science, University of Tokyo, Tokyo, Japan; 3 Universal Biology Institute, The University of Tokyo, Tokyo, Japan
GA-003 - The cytotoxic effect of Amblyomma sculptum tick saliva over cancer cell lines is associated with ΔΨm loss and cleavage of caspases-3 and caspase-9.
Cogo, S.1; França, N.1; Cambri, G.1; Micheau, O. 2; Simons, S. 3; Elifio-Esposito, S1.
1 Programa de Pós-graduação em Ciências da Saúde, Pontifícia Universidade Católica do Paraná, Curitiba - PR, Brazil.; 2 UFR Science de Santé, Université de Bourgogne Franche-Comté, Dijon, France.; 3Departamento de Parasitologia, Instituto Butantan, São Paulo - SP, Brazil.
GC-011 - Investigation of pro and anti-apoptotic modulators during infection by pathogenic protozoa such as Trypanosoma cruzi and Leishmania amazonensis.
Chain, M.O.1; Nogueira, A.S, Neto, A.N., Maciel, I.O., Fagundes, T.M., Lopes, U.G., Silva, R., Mesquita, R.D., Carneiro, L.T., Nestal de Moraes, G., De-Melo, L.D.B.
1Dep. Biotechnology, Federal Institute of Education, Science and Technology, RJ, Brazil; 2Department of Hemato-Molecular and Cellular Oncology, National Cancer Institute, Brazil; 3Institute of Biophysics, Federal University of Rio de Janeiro, RJ, Brazil; 4Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, RJ, Brazil
GC-020 - Genomic analysis of antimicrobial resistance in OXA-23-producing Acinetobacter baumannii strains in Brazil
Souza, F.J.1; Aires, C.A.M.2
1Programa Multicêntrico de Pós-graduação em Bioquímica e Biologia Molecular da Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil; 2Departamento de Ciências da Saúde da Universidade Federal Rural do Semi-Árido, Mossoró, Brazil.
HA-019 - Albumin overload impairs albumin endocytosis in proximal tubule cells through increased O-GlcNAcylation
Silva-Aguiar R.P.1, Peruchetti D.B.1, Paz-Marzolo M.2, Pinheiro A.A.S1,3, Dias W.B.1, Caruso-Neves C.1,3,4
1Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, RJ, Brazil; 2Laboratorio de Tráfico Intracelular y Señalización, Depto de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile; 3Rio de Janeiro Innovation Network in Nanosystems for Health-NanoSAÚDE/FAPERJ, RJ, Brazil; 4National Institute of Science and Technology for Regenerative Medicine, RJ, Brazil
HA-029 - Effects of NT157 on tyrosine kinase signaling pathways in BCR-ABL1 T315I cells
Silvestrini, V.C.1,2; Vargas, A.P1,2; Masson, A.P1; Thomé, C.H2; Fonseca, N.P2,3; Fenerich, B.A.2,3; Silva, A.B.A2,3; Traina, F2,3; Faça, V.M. 1,2
1Dept. Biochemistry and Immunology, 2Cell-Based Therapy Center, Ribeirão Preto Blood Center, 3Department of Medical Images, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, Ribeirão Preto, SP, Brazil.
JA-006 - Biochemical characterization of the interaction between Fbxo7 and androgen (AR) and estrogen (ER) receptors
1Spagnol, V.; 2Santos, K. R.; 2Passos, P. M. S.; 2Correia, C. R. S. T. B.; 1,2Teixeira, F. R.
1Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo/SP, Brazil. 2Department of Genetics and Evolution, Federal University of Sao Carlos/SP, Brazil.
NB-005 - Estudo sobre a eficiência do radiofármaco PSMA-1007-18F na detecção do câncer de próstata em um estudo pré-clínico in vivo
Santos C.S.F. 1; Marumo, M.H.B2.; Santos, S.N.1; Araújo, E.B. 1
1Centro de Radiofarmácia, Instituto de Pesquisas Energéticas e Nucleares, Universidade de São Paulo, SP, Brasil; 2 Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, Universidade de São Paulo, SP, Brasil.
